SCHEMBL251773

SCHEMBL251773

O=C(O)c1ccc(Nc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
MAPK13 O15264 1/20 0.60
MAPK12 P53778 1/20 0.60
MAPK11 Q15759 1/20 0.60
MAPK14 Q16539 1/20 0.60
SRD5A2 P31213 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Phenylamino Benzoic Acid SCHEMBL70190 0.93 MAPK13 (0.72) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL9479471 0.93 MAPK13 (0.72) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL2127845 0.91 TYR (0.73) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL11177087 0.89 TSHR (0.74) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL22075935 0.89 MEN1 (0.62) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL1663524 0.89 MAPT (0.58) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL5460566 0.89 MITF (0.69) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL2127792 0.89 SMN1; SMN2 (0.74) TSHRTP53SRD5A2SMN1; SMN2NPC1
SCHEMBL5459443 0.89 AKR1C3 (0.64) TSHRTP53MAPK13MAPK12MAPK11
SCHEMBL1887153 0.87 NAPRT (0.64) TSHRTP53MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909618-A Organic long afterglow film material based on blue phosphorescence and preparation method and application thereof 河北石油职业技术大学 2024-11-08 CN claimed
CN-117986455-B Preparation method of thickening tackifier for oil field 东营江源化工有限公司 2024-05-31 CN claimed
CN-117986455-A Preparation method of thickening tackifier for oil field 东营江源化工有限公司 2024-05-07 CN claimed
CN-117159462-A Compound procaine penicillin suspension injection and preparation method thereof 开封嘉骏生物科技有限公司 2023-12-05 CN claimed
US-20070129433-A1 Diphenylamine derivatives MERCK PATENT GMBH (DE) 2007-06-07 US claimed
EP-1687253-A2 DIPHENYLAMINE DERIVATIVES Merk Patent Gmbh (DE) 2006-08-09 EP claimed
US-20060074214-A1 Reactive hot-melt adhesive KESSELMAYER MARK A 2006-04-06 US claimed
EP-1642915-A2 Reactive hot-melt adhesive Rohm and Haas Company (US) 2006-04-05 EP claimed
WO-2005051888-A2 DIPHENYLAMINE DERIVATIVES MERK PATENT GMBH (DE) 2005-06-09 WO claimed
US-20040086949-A1 Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof STATENS SERUM INSTITUT 2004-05-06 US claimed
EP-0623635-A1 Amine-functionalized polyester GENERAL ELECTRIC COMPANY (US) 1994-11-09 EP claimed
EP-0037403-B1 HEAT ACTIVATABLE ADHESIVE WITH IMPROVED TEMPERATURE RESISTANCE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-10-17 EP claimed
US-4452955-A TWO PARTS-UNSATURATED CARBOXYL MONOMER ACCELERATOR AND POLYMERIZATION INHIBITOR, AND REACTION PRODUCT OF ALDEHYDE AND AMINE MINNESOTA MINING & MANUFACTURING COMPANY (US) 1984-06-05 US claimed
US-4430479-A Heat activatable adhesive with improved temperature resistance MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-02-07 US claimed
US-4404345-A UNSATURATED CARBOXYL MONOMER, HALOGENATED PROMOTER, POLYMERIZATION INHIBITOR WITH REALTION PRODUCT OF ALDEHYDE AND AMINE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-13 US claimed
EP-0037403-A4 HEAT ACTIVATABLE ADHESIVE WITH IMPROVED TEMPERATURE RESISTANCE. MINNESOTA MINING & MFG (US) 1982-01-26 EP claimed
EP-0037403-A1 HEAT ACTIVATABLE ADHESIVE WITH IMPROVED TEMPERATURE RESISTANCE. MINNESOTA MINING & MFG (US) 1981-10-14 EP claimed
WO-1981000718-A1 HEAT ACTIVATABLE ADHESIVE WITH IMPROVED TEMPERATURE RESISTANCE MINNESOTA MINING & MFG (US) 1981-03-19 WO claimed
US-4173506-A Bonding method utilizing polyester adhesive exhibiting \"open time\ MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-11-06 US claimed
US-4059715-A Adhesive composition and sheet-like product formed therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-11-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129433-A1 Diphenylamine derivatives CCNY, CHKB, CHKA TSHR 2049/4885TP53 4323/4885MAPK13 872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.