Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | TP53 | P04637 | 3/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.81 |
| ▸ | THRB | P10828 | 1/20 | 0.81 |
| ▸ | ATP1A1 | P05023 | 13/20 | 0.71 |
| ▸ | ATP1B1 | P05026 | 13/20 | 0.71 |
| ▸ | ATP1B2 | P14415 | 13/20 | 0.71 |
| ▸ | ATP1A2 | P50993 | 13/20 | 0.71 |
| ▸ | ATP1B3 | P54709 | 13/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.71 |
| ▸ | STAT3 | P40763 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | RORC | P51449 | 1/20 | 0.71 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.71 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deslanoside SCHEMBL12840817 | 0.94 | MAPT (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Deslanoside SCHEMBL125311 | 0.94 | MAPT (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Deslanoside SCHEMBL125312 | 0.94 | MAPT (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Deslanoside SCHEMBL28142803 | 0.92 | MAPT (0.95) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Deslanoside SCHEMBL10633059 | 0.90 | MAPT (0.92) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Lanatoside C SCHEMBL23054706 | 0.90 | PAX8 (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Lanatoside C SCHEMBL15959375 | 0.90 | PAX8 (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Lanatoside C SCHEMBL18947801 | 0.90 | PAX8 (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Lanatoside C SCHEMBL20582682 | 0.90 | PAX8 (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 | |
| Lanatoside C SCHEMBL44110 | 0.90 | PAX8 (1.00) | MAPTLMNATP53SMN1; SMN2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110250297-A1 | Treatment of Hyperproliferative Disorders Using Cardiac Glycosides | EPICENTRX, INC. | 2011-10-13 | — | — | US | disclosed |