Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL249639 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL249116 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL249049 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL299997 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL9462510 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL8940231 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL1243215 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL1143384 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL16053153 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL2053140 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016174131-A1 | 4-EPI-ISOFAGOMINE ENANTIOMER DERIVATIVES FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES | DORPHAN S.A. (CH) | 2016-11-03 | — | — | WO | disclosed |
| EP-3088389-A1 | 4-EPI-ISOFAGOMINE DERIVATIVES | Dorphan S.A. (CH) | 2016-11-02 | — | — | EP | disclosed |
| US-8088924-B2 | Pyridone derivatives having a binding activity to the cannabinoid type 2 receptor | SHIONOGI & CO., LTD. (JP) | 2012-01-03 | — | — | US | disclosed |
| CN-1060847-A | Tylosin derivative and preparation method thereof | MERCIAN CORP (JP) | 1992-05-06 | — | — | CN | disclosed |
| EP-0482594-A1 | Tylosin derivative and method for preparing the same | MERCIAN CORPORATION (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-5093502-A | 14α,17α-dihydroxy-17β-substituted steroids | AKZO N.V. (NL) | 1992-03-03 | — | — | US | disclosed |