Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL249639 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL249116 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL249049 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL251831 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL9462510 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL8940231 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL1243215 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL1143384 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL16053153 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A | |
| Toluene SCHEMBL2053140 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2CTBP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410577-B1 | — | — | None | — | — | US | disclosed |
| CN-104272148-B | The manufacture method of phase retardation film, polaroid and liquid crystal indicator | 柯尼卡美能达株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-104272148-A | Method for producing phase difference film, polarizing plate, and liquid crystal display device | KONICA MINOLTA INC | 2015-01-07 | — | — | CN | disclosed |
| CN-101511799-B | Cyclic amine compound | DAIICHI SANKYO CO LTD | 2012-05-30 | — | — | CN | disclosed |
| EP-1160252-B1 | AVERMECTIN DERIVATIVES | KITASATO INST (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8158790-B2 | Cyclic amine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2036896-B1 | CYCLIC AMINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-2358369-A1 | Process for the preparation of substantially optically pure repaglinide and precursors thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2011-08-24 | — | — | EP | disclosed |
| EP-2332949-A1 | Avermectin derivatives | The Kitasato Institute (JP) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010046360-A1 | PROCESS FOR THE PREPARATION OF SUBSTANTIALLY OPTICALLY PURE REPAGLINIDE AND PRECURSORS THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2010-04-29 | — | — | WO | disclosed |
| CN-1346362-A | Avermectin derivatives | KITASATO INST (JP) | 2002-04-24 | — | — | CN | disclosed |
| EP-1160252-A1 | AVERMECTIN DERIVATIVES | THE KITASATO INSTITUTE (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-20010031752-A1 | Substituted 8,8a-dihydro-3ah-indeno[1,2-d]thiazoles, processes for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2001-10-18 | — | — | US | disclosed |
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-6143769-A | ENANTIOMORPH | KARL THOMAE GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| CN-1048722-C | (S)(+)-2-Ethoxy-4-[N-[1-(2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbonylmethyl]-benzoic acid, pharmaceutical compositions containing compound and processes for preparation thereof | THOMAE GMBH DR K (DE) | 2000-01-26 | — | — | CN | disclosed |
| CN-1238761-A | benzamide aldehydes and their use as cysteine protease inhibitors | BASF AG (DE) | 1999-12-15 | — | — | CN | disclosed |
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| CN-1152918-A | Novel amido quinoxaline diones, their preparation and use | BASF AG (DE) | 1997-06-25 | — | — | CN | disclosed |
| CN-1068820-A | (S) (+)-2-oxyethyl group-4-[N-[1-(2-piperidino-phenyl)-3-methyl isophthalic acid-butyl] amino carbonyl methyl] phenylformic acid, contain pharmaceutical composition of this compound and preparation method thereof | THOMAE GMBH DR K (DE) | 1993-02-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031752-A1 | Substituted 8,8a-dihydro-3ah-indeno[1,2-d]thiazoles, processes for their preparation and their use as medicaments | ALDH5A1, CYP11B1, CYP11B2 | L3MBTL1 4476/4885TDP1 1415/4885SMN1; SMN2 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.