SCHEMBL251840

SCHEMBL251840

O=C(C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 6/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
EPHX1 P07099 1/20 0.46
EPHX2 P34913 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HTT P42858 2/20 0.45
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
GLA P06280 1/20 0.45
TSHR P16473 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GAA P10253 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
XBP1 P17861 1/20 0.42
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11787415 0.97 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL19557166 0.79 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL133056 0.79 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL12714 0.79 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL19557168 0.79 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL546352 0.79 HTT (0.48) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL3101322 0.77 HSD11B1 (0.46) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL5487136 0.77 HSD11B1 (0.46) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL5489940 0.77 HSD11B1 (0.46) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL4389277 0.77 HSD11B1 (0.46) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894207-B Synthesis method of 2- (3-hydroxy-1-adamantane) -2-oxo acetic acid 南京康立瑞生物科技有限公司 2025-05-02 CN claimed
CN-117440992-A Use of a composition in optical measurement applications F2MB-工程公司 2024-01-23 CN claimed
CN-115894207-A Synthesis method of 2- (3-hydroxy-1-adamantane) -2-oxoacetic acid 南京康立瑞生物科技有限公司 2023-04-04 CN claimed
CN-108707162-B Keto hydroboration reaction method under catalyst-free and solvent-free conditions 南京林业大学 2020-09-01 CN claimed
CN-110615771-A Method for directly synthesizing furazan oxide from methyl ketone 中国科学院青岛生物能源与过程研究所 2019-12-27 CN claimed
CN-108707162-A A kind of ketone hydroboration method under the conditions of no catalyst or solvent 南京林业大学 2018-10-26 CN claimed
CN-107353226-A A kind of synthetic method of two adamantane azine 湖北航天化学技术研究所 2017-11-17 CN claimed
CN-103846103-A Silica gel loaded type catalyst and application of catalyst in Baeyer-Villiger reaction UNIV NANJING SCIENCE & TECH 2014-06-11 CN claimed
EP-1337229-B1 IMMOBILISATION OF ACTIVE AGENTS ON FIBRES HENKEL AG & CO KGAA (DE) 2009-09-30 EP claimed
CN-101411974-A Process for synthesizing mesoporous magnesia catalyst and uses thereof UNIV FUDAN (CN) 2009-04-22 CN claimed
EP-1043298-A1 PROCESSES FOR THE PREPARATION OF ALCOHOLS Daicel Chemical Industries, Ltd. (JP) 2000-10-11 EP claimed
JP-5339225-A None JP disclosed
CN-115894207-B Synthesis method of 2- (3-hydroxy-1-adamantane) -2-oxo acetic acid 南京康立瑞生物科技有限公司 2025-05-02 CN disclosed
CN-119798213-A Alpha-hydroxycarboxylic acid derivative with adamantyl, and preparation method and application thereof 黄淮学院 2025-04-11 CN disclosed
CN-114507124-B Separation method of 2-adamantanone 浙江荣耀生物科技股份有限公司 2024-06-18 CN disclosed
CN-1185757-A Oxidation catalyst system and oxidation process using the same DAICEL CHEM (JP) 1998-06-24 CN disclosed
JP-H05339225-A 1-(1'-CYANOETHENYL)ADAMANTAN AND RESIST MATERIAL FUJITSU LTD 1993-12-21 JP disclosed
EP-0490631-A2 Ion-selective electrodes Harris, Steven J. (IE) 1992-06-17 EP disclosed
US-4220606-A Cyclic hydrocarbon perfluorination process SUNTECH, INC. (US) 1980-09-02 US disclosed
US-3961074-A ANTICARIES AGENTS COLGATE-PALMOLIVE COMPANY (US) 1976-06-01 US disclosed