SCHEMBL133056

SCHEMBL133056

O=C(Cl)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
ALDH1A1 P00352 3/20 0.44
POLB P06746 1/20 0.44
HTT P42858 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
GLA P06280 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
THRB P10828 1/20 0.41
XBP1 P17861 1/20 0.41
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21439790 0.91
SCHEMBL7974713 0.87 HSD11B1 (0.39) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL692431 0.83 SMN1; SMN2 (0.52) HSD11B1L3MBTL1ALDH1A1GAAMEN1
SCHEMBL24846052 0.83 ALDH1A1 (0.47) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL24202563 0.83 HSD11B1 (0.37) HSD11B1L3MBTL1ALDH1A1POLBHTT
SCHEMBL3188989 0.81 HSD11B1 (0.56) HSD11B1ALDH1A1KDM4EGAAMEN1
SCHEMBL4580828 0.80 SMN1; SMN2 (0.43) HSD11B1L3MBTL1ALDH1A1HTTCRHBP
SCHEMBL1398388 0.79 EPHX2 (0.52) HSD11B1L3MBTL1EPHX2ALDH1A1POLB
SCHEMBL28428330 0.79 HSD11B1 (0.34) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1
SCHEMBL251840 0.79 HSD11B1 (0.50) HSD11B1L3MBTL1EPHX1EPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2270 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460126-B2 Quantum dot, method of preparing the quantum dot, composition including the quantum dot, optical member including the quantum dot, and electronic apparatus including the quantum dot SAMSUNG DISPLAY CO., LTD. (KR) 2025-11-04 US claimed
CN-118719157-A Polymer-based photocatalytic material and preparation method and application thereof 西北民族大学 2024-10-01 CN claimed
CN-118496175-A TRADD inhibitor derivative and preparation method and application thereof 安徽医科大学 2024-08-16 CN claimed
CN-118459372-A Preparation method of photoacid generator sulfonate for ARF photoresist 常州朗芯新材料科技有限公司 2024-08-09 CN claimed
CN-114573802-B Surfactant and preparation method thereof 中国石油天然气股份有限公司 2024-03-26 CN claimed
CN-116492480-A Preparation method and application of cyclodextrin-metal organic framework carrier platform composite nano material capable of loading contrast agent 浙江大学 2023-07-28 CN claimed
CN-116459206-A Construction and application of calcium alginate hydrogel system loaded with CCL25 chemokine and anti-PDL 1 antibody 华南理工大学 2023-07-21 CN claimed
US-20230192751-A1 METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2023-06-22 US claimed
CN-114149421-B Palmatine derivatives, preparation method and antithrombotic use thereof 中国医学科学院医药生物技术研究所 2023-04-25 CN claimed
CN-115093736-B Antibacterial and anti-fingerprint liquid for touch screen panel and preparation method thereof 深圳市中仁能源科技有限公司 2023-04-07 CN claimed
WO-1999015540-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1999-04-01 WO claimed
EP-0565732-B1 BENZODIOXANE DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 1998-01-14 EP claimed
EP-0638060-A4 T-BUTYL CASCADE POLYMERS. UNIV SOUTH FLORIDA (US) 1995-04-19 EP claimed
EP-0638060-A1 T-BUTYL CASCADE POLYMERS UNIVERSITY OF SOUTH FLORIDA (US) 1995-02-15 EP claimed
WO-1993021144-A1 T-BUTYL CASCADE POLYMERS UNIVERSITY OF SOUTH FLORIDA (US) 1993-10-28 WO claimed
WO-1991018002-A1 NUCLEOSIDES AS SYNTHONES FOR RNA-SYNTHESIS DIAGEN INSTITUT FÜR MOLEKULARBIOLOGISCHE DIAGNOSTIK GMBH (DE) 1991-11-28 WO claimed
US-4359461-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1982-11-16 US claimed
US-4359460-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1982-11-16 US claimed
US-4123447-A REACTING (1,5-CYCLOOCTADIENE)BIS(TRIETHYLPHOSPHINE)-NICKEL(O) WITH AN ACYL HALIDE, OLIGOMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1978-10-31 US claimed
US-4088668-A Acetylene derivatives MERRELL TORAUDE ET COMPAGNIE (FR) 1978-05-09 US claimed