SCHEMBL25184972

SCHEMBL25184972

O=C(/C=C/c1ccc(OCCO)cc1)c1ccc(Br)cc1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 7/20 0.73
▸ MAOA P21397 1/20 0.66
▸ ABCG2 Q9UNQ0 3/20 0.60
▸ ESR1 P03372 1/20 0.60
▸ ESR2 Q92731 1/20 0.60
▸ CYP1B1 Q16678 2/20 0.57
▸ HRH3 Q9Y5N1 1/20 0.55
▸ CYP1A1 P04798 1/20 0.55
▸ MAPT P10636 2/20 0.55
▸ MEN1 O00255 1/20 0.54
▸ USP2 O75604 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ RECQL P46063 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ TLR9 Q9NR96 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25185066 1.00 MAOB (0.73) MAOBMAOAABCG2ESR1ESR2
SCHEMBL25198017 0.93 ABCG2 (0.68) MAOBMAOAABCG2CYP1B1HRH3
SCHEMBL29574815 0.89 MAOB (0.73) MAOBMAOAABCG2ESR1ESR2
SCHEMBL29014252 0.88 MAOB (0.71) MAOBMAOAABCG2ESR1ESR2
SCHEMBL29014173 0.88 MAOB (0.71) MAOBMAOAABCG2ESR1ESR2
SCHEMBL29181747 0.88 MAOB (0.71) MAOBMAOAABCG2ESR1ESR2
SCHEMBL25265080 0.87 ABCG2 (0.61) MAOBMAOAABCG2CYP1B1HRH3
SCHEMBL25194929 0.87 ABCG2 (0.61) MAOBMAOAABCG2CYP1B1HRH3
SCHEMBL25190838 0.86 MAOB (0.70) MAOBMAOAABCG2ESR1ESR2
SCHEMBL25204034 0.86 MAOB (0.73) MAOBMAOAABCG2CYP1B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885MAOA 1902/4885ABCG2 1606/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAOA 3145/4885ABCG2 3622/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAOA 3145/4885ABCG2 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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