SCHEMBL251865

SCHEMBL251865

O=C1NN=C(c2ccccc2)CO1

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 18/20 0.67
PDE3A Q14432 18/20 0.67
AXL P30530 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261632 0.82 PDE3A (0.65) PDE3BPDE3A
SCHEMBL4649731 0.82 PDE3B (0.59) PDE3BPDE3A
SCHEMBL4693648 0.82 PDE3B (0.70) PDE3BPDE3A
SCHEMBL7976918 0.82 PDE3B (0.70) PDE3BPDE3A
SCHEMBL7112822 0.82 PDE3B (0.50) PDE3BPDE3A
SCHEMBL20703338 0.81 PDE3B (1.00) PDE3BPDE3A
SCHEMBL20702748 0.81 PDE3B (1.00) PDE3BPDE3A
SCHEMBL10781852 0.80 PDE3A (0.62) PDE3BPDE3A
SCHEMBL9669173 0.78 PDE3B (0.52) PDE3BPDE3A
SCHEMBL9668972 0.78 PDE3B (0.58) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877513-B1 CAP LINERS, CLOSURES AND GASKETS FROM MULTI-BLOCK POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-08 EP claimed
US-10196494-B2 Polymeric sheets, methods for making and using the same, and articles comprising polymeric sheets SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-05 US claimed
US-20160002429-A1 POLYMERIC SHEETS, METHODS FOR MAKING AND USING THE SAME, AND ARTICLES COMPRISING POLYMERIC SHEETS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-07 US claimed
EP-2958957-A1 POLYMERIC SHEETS, METHODS FOR MAKING AND USING THE SAME, AND ARTICLES COMPRISING POLYMERIC SHEETS SABIC Global Technologies B.V. (NL) 2015-12-30 EP claimed
WO-2014130751-A1 POLYMERIC SHEETS, METHODS FOR MAKING AND USING THE SAME, AND ARTICLES COMPRISING POLYMERIC SHEETS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-08-28 WO claimed
US-7671106-B2 Cap liners, closures and gaskets from multi-block polymers DOW GLOBAL TECHNOLOGIES INC. (US) 2010-03-02 US claimed
JP-2008545017-A 2008-12-11 JP claimed
EP-1877513-A2 CAP LINERS, CLOSURES AND GASKETS FROM MULTI-BLOCK POLYMERS Dow Global Technologies Inc. (US) 2008-01-16 EP claimed
WO-2006113000-A2 CAP LINERS, CLOSURES AND GASKETS FROM MULTI-BLOCK POLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-10-26 WO claimed
US-20060199911-A1 Cap liners, closures and gaskets from multi-block polymers DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US claimed
US-4683247-A Foamable thermoplastic compositions, foamed articles and foaming method based on pre-compounded nucleating agent-resin concentrate GENERAL ELECTRIC COMPANY (US) 1987-07-28 US claimed
EP-0181000-A2 Foamable polyetherimide resin formulation GENERAL ELECTRIC COMPANY (US) 1986-05-14 EP claimed
US-4587272-A Foamable polycarbonate compositions, articles and methods GENERAL ELECTRIC COMPANY (US) 1986-05-06 US claimed
EP-0158266-A2 Foamable polycarbonate compositions, articles and methods GENERAL ELECTRIC COMPANY (US) 1985-10-16 EP claimed
US-4544677-A IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1985-10-01 US claimed
US-4543368-A DIHYDRODIAZINONE BLOWING AGENT GENERAL ELECTRIC COMPANY (US) 1985-09-24 US claimed
US-4334030-A INJECTION MOLDABLE CONCENTRATES CONTAINING AMIDE DERIVATIVES OF AZODICARBOXYLIC ACID AND A DIHYDROOXADIAZINONE AS BLOWING AGENTS GENERAL ELECTRIC COMPANY (US) 1982-06-08 US claimed
US-4163037-A USING A DIHYDROOXADIAZINONE BLOWING AGENT, INJECTION MOLDING GENERAL ELECTRIC COMPANY (US) 1979-07-31 US claimed
US-4097671-A 5-PHENYL-3,6-DIHYDRO-1,3,4-OXADIAZIN-2-ONE, THERMOPLASTIC POLYMER BLOWING AGENT GENERAL ELECTRIC COMPANY (US) 1978-06-27 US claimed
US-4097425-A POLYCARBONATES, POLYESTERS, SUBSTITUTED 3,6-DIHYDRO-1,3,4-OXDIAZIN-2-ONE GENERAL ELECTRIC COMPANY (US) 1978-06-27 US claimed