Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20703004 | 0.83 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL4649731 | 0.83 | PDE3B (0.59) | PDE3BPDE3A | |
| SCHEMBL4693648 | 0.83 | PDE3B (0.70) | PDE3BPDE3A | |
| SCHEMBL261632 | 0.83 | PDE3A (0.65) | PDE3BPDE3A | |
| SCHEMBL251865 | 0.82 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL9669173 | 0.82 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL20705321 | 0.80 | PDE3B (1.00) | PDE3BPDE3A | |
| SCHEMBL7979367 | 0.78 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11248109 | 0.76 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL20702701 | 0.76 | PDE3B (0.86) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000601-A1 | NOVEL 4-(2-OXODIHYDROOXADIAZINYLPHENYL)AMIDES AND THE USE THEREOF FOR TREATING ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |
| EP-0223937-B1 | INDOLES SUBSTITUTED WITH HETEROCYCLES, INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4851406-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0223937-A1 | Indoles substituted with heterocycles, intermediates, process for their preparation and medicaments | Roche Diagnostics GmbH (DE) | 1987-06-03 | — | — | EP | disclosed |