Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481290 | 1.00 | TSHR (0.81) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL10481289 | 0.91 | TSHR (0.77) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL28054469 | 0.90 | TSHR (1.00) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| Dimethyl Succinate SCHEMBL10213 | 0.90 | TSHR (1.00) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL14092783 | 0.89 | TSHR (0.65) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL9736888 | 0.89 | TSHR (0.65) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL8038535 | 0.89 | TSHR (0.67) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL22472185 | 0.89 | TSHR (0.75) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL16972752 | 0.89 | TSHR (0.65) | TSHRLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL29209613 | 0.89 | TSHR (0.65) | TSHRLMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907341-A | Pyridopyrimidinone derivatives, and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114805434-A | Novel tetradentate phosphine ligand compound and synthetic method and application thereof | 惠州凯特立斯科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-110699195-B | Degumming composition and preparation method and application thereof | 义乌欧风汽车用品有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-110791389-B | Degumming agent and preparation method and application thereof | 义乌欧风汽车用品有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-109467514-B | Synthetic method of alpha-amino-gamma-carbonyl pimelate compound | 西北师范大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110791389-A | Environment-friendly adhesive remover and preparation method and application thereof | 义乌欧风汽车用品有限公司 | 2020-02-14 | — | — | CN | disclosed |
| CN-110699195-A | Degumming composition and preparation method and application thereof | 义乌欧风汽车用品有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-109467514-A | A kind of synthetic method of α-amido-gamma-carbonyl group pimelic acid ester type compound | 西北师范大学 | 2019-03-15 | — | — | CN | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| US-4914176-A | Poly(heterocyclic) polymers | SHELL OIL COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0359341-A2 | 1,6-diazaspiro[4,4]nonane-2,7-dione derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
| EP-0359340-A2 | Spirodilactam polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
| US-4908458-A | 1,5-Di(benzoheterocyclic)-3-oxopentane derivatives | SHELL OIL COMPANY (US) | 1990-03-13 | — | — | US | disclosed |
| US-4885351-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0342664-A2 | 2,2-disubstituted benzopyran leukotriene-D4 antagonists | G.D. Searle & Co. (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0336475-A1 | 1,6-diazaspiro (4,4)nonane-2,7-dione derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-10-11 | — | — | EP | disclosed |
| EP-0334455-A1 | Process for the production of keto-diesters | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-09-27 | — | — | EP | disclosed |
| US-4849542-A | Process for the preparation of oxo-alkanedioic acids or diesters thereof | SHELL OIL COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4800231-A | Keto-diesters production | SHELL OIL COMPANY (US) | 1989-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | TSHR 2718/4885LMNA 2643/4885KDM4E 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.