Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777193 | 0.93 | CCR5 (0.67) | CCR5 | |
| SCHEMBL4775197 | 0.85 | NPSR1 (0.56) | CCR5 | |
| SCHEMBL2519138 | 0.85 | CCR5 (0.67) | CCR5KCNH2 | |
| SCHEMBL4768738 | 0.84 | POLB (0.56) | CCR5 | |
| SCHEMBL2519151 | 0.84 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL14436618 | 0.84 | CCR5 (0.56) | CCR5KCNH2 | |
| SCHEMBL4777713 | 0.81 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL4768582 | 0.81 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL3034563 | 0.80 | CCR5 (0.90) | CCR5KCNH2 | |
| SCHEMBL30227460 | 0.80 | CCR5 (0.90) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410094-B2 | Amide compounds, their pharmaceutical compositions, their preparation method and their uses | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2013-04-02 | — | — | US | disclosed |
| US-20110251192-A1 | AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR PREPARATION METHOD AND THEIR USES | SHANGHAI TARGETDRUG CO., LTD. (CN) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251192-A1 | AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR PREPARATION METHOD AND THEIR USES | CCR5, CCR8, CXCR1 | CCR5 1/4885KCNH2 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.