Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519138 | 0.86 | CCR5 (0.67) | CCR5KCNH2 | |
| SCHEMBL14436618 | 0.85 | CCR5 (0.56) | CCR5KCNH2 | |
| SCHEMBL2518892 | 0.84 | CCR5 (0.61) | CCR5KCNH2 | |
| SCHEMBL13326726 | 0.81 | CCR5 (0.52) | CCR5KCNH2 | |
| SCHEMBL2518706 | 0.80 | CCR5 (0.50) | CCR5KCNH2 | |
| SCHEMBL16503435 | 0.80 | CCR5 (0.56) | CCR5 | |
| SCHEMBL4773903 | 0.78 | CCR5 (0.67) | CCR5KCNH2 | |
| SCHEMBL14456199 | 0.77 | CCR5 (0.56) | CCR5KCNH2 | |
| SCHEMBL4777193 | 0.76 | CCR5 (0.67) | CCR5 | |
| SCHEMBL14434728 | 0.76 | CCR5 (0.51) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410094-B2 | Amide compounds, their pharmaceutical compositions, their preparation method and their uses | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2013-04-02 | — | — | US | disclosed |
| US-8410094-B2 | Amide compounds, their pharmaceutical compositions, their preparation method and their uses | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2013-04-02 | — | — | US | disclosed |
| US-8410094-B2 | Amide compounds, their pharmaceutical compositions, their preparation method and their uses | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2013-04-02 | — | — | US | disclosed |
| US-20110251192-A1 | AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR PREPARATION METHOD AND THEIR USES | SHANGHAI TARGETDRUG CO., LTD. (CN) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251192-A1 | AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR PREPARATION METHOD AND THEIR USES | CCR5, CCR8, CXCR1 | CCR5 1/4885KCNH2 2261/4885ACHE 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.