SCHEMBL25189693

SCHEMBL25189693

CCCCCC(CCCCC)CCCOC(=O)CCCCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
TDP1 Q9NUW8 1/20 0.48
DGKA P23743 1/20 0.47
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
EPHX2 P34913 4/20 0.44
ACHE P22303 6/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
TPSAB1 Q15661 1/20 0.42
TPSD1 Q9BZJ3 1/20 0.42
TPSG1 Q9NRR2 1/20 0.42
EPHX1 P07099 1/20 0.42
DNM1 Q05193 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23115366 0.96 CA12 (0.46) CA12CA1CA2CA9TDP1
SCHEMBL25239638 0.94 CA12 (0.44) CA12CA1CA2CA9TDP1
SCHEMBL25201565 0.94 CA12 (0.44) CA12CA1CA2CA9TDP1
SCHEMBL25204665 0.94 CA12 (0.44) CA12CA1CA2CA9TDP1
SCHEMBL23115411 0.91 TDP1 (0.42) CA12CA1CA2CA9TDP1
SCHEMBL23115414 0.91 MAOA (0.45) CA12CA1CA2CA9TDP1
SCHEMBL31284031 0.90 CA12 (0.59) CA12CA1CA2CA9TDP1
SCHEMBL25181487 0.90 CA12 (0.59) CA12CA1CA2CA9TDP1
SCHEMBL31357657 0.89 TDP1 (0.51) CA12CA1CA2CA9TDP1
SCHEMBL31325275 0.89 TDP1 (0.51) CA12CA1CA2CA9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051263-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SAIL BIOMEDICINES, INC. 2025-02-13 US disclosed
EP-4436549-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME Sail Biomedicines, Inc. (US) 2024-10-02 EP disclosed
WO-2023091787-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2023-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051263-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME NPC1L1, ABCB4, LIPA CA12 1271/4885CA1 2457/4885CA2 1767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.