SCHEMBL25190664

SCHEMBL25190664

COc1ccc(C(=O)/C=C/c2ccc(OCC(=O)O)c(OC)c2)c(OC)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 5/20 0.78
▸ MAPT P10636 4/20 0.67
▸ TNFRSF1A P19438 1/20 0.67
▸ ALOX5 P09917 1/20 0.65
▸ MEN1 O00255 3/20 0.65
▸ KMT2A Q03164 3/20 0.65
▸ PDE4A P27815 2/20 0.65
▸ PDE4B Q07343 2/20 0.65
▸ PDE4C Q08493 2/20 0.65
▸ PDE4D Q08499 2/20 0.65
▸ NPC1 O15118 1/20 0.65
▸ RAB9A P51151 1/20 0.65
▸ FLT3 P36888 1/20 0.64
▸ XDH P47989 1/20 0.63
▸ HDAC1 Q13547 1/20 0.63
▸ HDAC2 Q92769 1/20 0.63
▸ HDAC8 Q9BY41 1/20 0.63
▸ POLB P06746 1/20 0.62
▸ APP P05067 3/20 0.62
▸ NR1I2 O75469 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25193188 0.90 ABCG2 (0.78) ABCG2MAPTTNFRSF1AMEN1KMT2A
SCHEMBL25200344 0.90 ABCG2 (0.78) ABCG2MAPTTNFRSF1AMEN1KMT2A
SCHEMBL30383330 0.88 ALOX5 (0.84) ABCG2MAPTALOX5MEN1KMT2A
SCHEMBL10546492 0.88 ALOX5 (0.62) ABCG2MAPTTNFRSF1AALOX5MEN1
SCHEMBL10543994 0.88 ALOX5 (0.84) ABCG2MAPTALOX5MEN1KMT2A
SCHEMBL30384135 0.88 ALOX5 (0.62) ABCG2MAPTTNFRSF1AALOX5MEN1
SCHEMBL10546469 0.88 ALOX5 (0.62) ABCG2MAPTTNFRSF1AALOX5MEN1
SCHEMBL21527670 0.88 ABCG2 (1.00) ABCG2MAPTTNFRSF1AALOX5MEN1
SCHEMBL21527669 0.88 ABCG2 (1.00) ABCG2MAPTTNFRSF1AALOX5MEN1
SCHEMBL25195265 0.86 TNFRSF1A (0.77) ABCG2MAPTTNFRSF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAPT 3297/4885TNFRSF1A 2669/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAPT 3512/4885TNFRSF1A 3485/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAPT 3512/4885TNFRSF1A 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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