SCHEMBL25190822

SCHEMBL25190822

O=C(/C=C/c1cccc(OC(F)(F)C(F)F)c1)c1ccc(O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 5/20 0.62
BCHE P06276 3/20 0.59
MAOB P27338 3/20 0.54
RELA Q04206 1/20 0.53
CYP1B1 Q16678 3/20 0.52
F3 P13726 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH2 P05091 1/20 0.52
CYP3A4 P08684 1/20 0.52
HSPD1 P10809 1/20 0.52
CYP19A1 P11511 1/20 0.52
MAOA P21397 1/20 0.52
HSPE1 P61604 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP1A1 P04798 2/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
NR1H4 Q96RI1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25203590 0.89 P4HB (0.70) P4HBBCHEMAOBRELACYP1B1
SCHEMBL25206648 0.85 ABCG2 (0.67) P4HBMAOBRELAMAPTMEN1
SCHEMBL2646518 0.81 MAOB (0.64) P4HBBCHEMAOBCYP1B1MAPT
SCHEMBL25219562 0.79 MAOB (0.84) P4HBBCHEMAOBCYP1B1F3
SCHEMBL25190646 0.79 MAOB (0.84) P4HBBCHEMAOBCYP1B1F3
SCHEMBL2999489 0.78 F3 (0.72) P4HBBCHEMAOBRELACYP1B1
SCHEMBL2999487 0.78 F3 (0.72) P4HBBCHEMAOBRELACYP1B1
SCHEMBL31233167 0.78 F3 (0.72) P4HBBCHEMAOBRELACYP1B1
SCHEMBL25193892 0.78 KMT2A (0.77) P4HBBCHEMAOBRELACYP1B1
SCHEMBL25206171 0.78 MAOB (0.68) P4HBBCHEMAOBRELACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B P4HB 552/4885BCHE 588/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885BCHE 465/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 P4HB 469/4885BCHE 465/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.