SCHEMBL25190825

SCHEMBL25190825

Cc1ccccc1S(=O)(=O)Nc1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
MAOA P21397 2/20 0.54
MAOB P27338 2/20 0.54
RAB9A P51151 2/20 0.54
POLB P06746 1/20 0.54
F3 P13726 2/20 0.54
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
CYP3A4 P08684 2/20 0.53
HSPD1 P10809 2/20 0.53
HSPE1 P61604 2/20 0.53
PKM P14618 1/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
ALDH2 P05091 1/20 0.53
CYP19A1 P11511 1/20 0.53
CYP1B1 Q16678 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25202136 0.86 MAOB (0.51) MAPTMAOAMAOBRAB9APOLB
SCHEMBL3484363 0.86 F3 (0.54) MAPTMAOAMAOBRAB9AF3
SCHEMBL30383944 0.86 F3 (0.54) MAPTMAOAMAOBRAB9AF3
SCHEMBL30384281 0.86 F3 (0.54) MAPTMAOAMAOBRAB9APOLB
SCHEMBL3484366 0.86 F3 (0.54) MAPTMAOAMAOBRAB9AF3
SCHEMBL3484449 0.86 F3 (0.54) MAPTMAOAMAOBRAB9APOLB
SCHEMBL25197330 0.86 ESR1 (0.54) MAPTMAOAMAOBRAB9APOLB
SCHEMBL25195314 0.86 MAOB (0.54) MAPTMAOAMAOBRAB9AF3
SCHEMBL3484447 0.86 F3 (0.54) MAPTMAOAMAOBRAB9APOLB
SCHEMBL25191826 0.84 ABCG2 (0.52) MAPTMAOAMAOBRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAOA 1902/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOA 3145/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAOA 3145/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.