SCHEMBL25202136

SCHEMBL25202136

CCc1ccccc1S(=O)(=O)Nc1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.51
F3 P13726 2/20 0.51
CYP3A4 P08684 2/20 0.51
HSPD1 P10809 2/20 0.51
HSPE1 P61604 2/20 0.51
KMT2A Q03164 2/20 0.51
RAB9A P51151 2/20 0.51
MAPT P10636 2/20 0.51
MAOA P21397 2/20 0.51
PKM P14618 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
MEN1 O00255 1/20 0.51
ALDH2 P05091 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP1B1 Q16678 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
ABCG2 Q9UNQ0 3/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25191826 0.88 ABCG2 (0.52) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL30384570 0.88 ABCG2 (0.52) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL25190825 0.86 MAPT (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL3484363 0.84 F3 (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL3484366 0.84 F3 (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL30384281 0.84 F3 (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL25195314 0.84 MAOB (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL25197330 0.84 ESR1 (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL3484447 0.84 F3 (0.54) MAOBF3CYP3A4HSPD1HSPE1
SCHEMBL30383944 0.84 F3 (0.54) MAOBF3CYP3A4HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885F3 5/4885CYP3A4 928/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885CYP3A4 1589/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885CYP3A4 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.