SCHEMBL25190877

SCHEMBL25190877

CS(=O)(=O)c1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.75
F3 P13726 3/20 0.74
MAPT P10636 5/20 0.69
RAB9A P51151 4/20 0.69
MAOA P21397 2/20 0.69
POLB P06746 1/20 0.69
PTGS2 P35354 3/20 0.65
ESR1 P03372 1/20 0.64
ESR2 Q92731 1/20 0.64
CXCL12 P48061 1/20 0.64
KMT2A Q03164 4/20 0.63
MEN1 O00255 3/20 0.63
ALDH1A1 P00352 2/20 0.63
P4HB P07237 1/20 0.63
CALM1 P0DP23 1/20 0.63
XDH P47989 1/20 0.63
LMNA P02545 1/20 0.63
GAA P10253 1/20 0.63
CASP3 P42574 1/20 0.63
SENP8 Q96LD8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787169 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL10703657 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL773589 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL25211913 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL25236411 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL773588 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL25223420 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL25202156 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL11815086 0.86 MAOB (1.00) MAOBMAOAPTGS2CXCL12CYP1B1
SCHEMBL11815082 0.86 MAOB (1.00) MAOBMAOAPTGS2CXCL12CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885F3 5/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.