SCHEMBL25190877

SCHEMBL25190877

CS(=O)(=O)c1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 4/20 0.75
▸ F3 P13726 3/20 0.74
▸ MAPT P10636 5/20 0.69
▸ RAB9A P51151 4/20 0.69
▸ MAOA P21397 2/20 0.69
▸ POLB P06746 1/20 0.69
▸ PTGS2 P35354 3/20 0.65
▸ ESR1 P03372 1/20 0.64
▸ ESR2 Q92731 1/20 0.64
▸ CXCL12 P48061 1/20 0.64
▸ KMT2A Q03164 4/20 0.63
▸ MEN1 O00255 3/20 0.63
▸ ALDH1A1 P00352 2/20 0.63
▸ P4HB P07237 1/20 0.63
▸ CALM1 P0DP23 1/20 0.63
▸ XDH P47989 1/20 0.63
▸ LMNA P02545 1/20 0.63
▸ GAA P10253 1/20 0.63
▸ CASP3 P42574 1/20 0.63
▸ SENP8 Q96LD8 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4,4'-Dihydroxychalcone SCHEMBL773588 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL10703657 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL10787169 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL25211913 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL25236411 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL773589 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL25223420 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
4,4'-Dihydroxychalcone SCHEMBL25202156 0.86 F3 (1.00) MAOBF3MAPTRAB9AMAOA
SCHEMBL11815082 0.86 MAOB (1.00) MAOBMAOAPTGS2CXCL12CYP1B1
SCHEMBL11815086 0.86 MAOB (1.00) MAOBMAOAPTGS2CXCL12CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885F3 5/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885F3 11/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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