Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 9/20 | 0.54 |
| ▸ | LATS2 | Q9NRM7 | 5/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25184747 | 0.96 | LATS1 (0.55) | LATS1LATS2APPNPY1RNPY5R | |
| SCHEMBL26157393 | 0.78 | LATS1 (0.68) | LATS1LATS2APPTLR8 | |
| SCHEMBL26157394 | 0.74 | LATS1 (0.69) | LATS1LATS2APPTLR8 | |
| SCHEMBL24038281 | 0.72 | APP (0.70) | APPNPY5R | |
| SCHEMBL26177090 | 0.70 | LATS1 (1.00) | LATS1LATS2 | |
| SCHEMBL250853 | 0.69 | ACHE (0.42) | LATS1LATS2KDM4C | |
| SCHEMBL26157392 | 0.69 | LATS1 (0.67) | LATS1LATS2APP | |
| SCHEMBL23260499 | 0.69 | NPY5R (0.46) | APPNPY1RNPY5R | |
| SCHEMBL26157957 | 0.68 | DCPS (0.55) | — | |
| SCHEMBL8891182 | 0.68 | APP (0.63) | APPNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |