SCHEMBL25191765

SCHEMBL25191765

COc1ccc(C=CC(=O)c2ccc(O)cc2)cc1COc1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 1.00
▸ MEN1 O00255 7/20 1.00
▸ ALDH1A1 P00352 6/20 1.00
▸ LMNA P02545 6/20 1.00
▸ KDM4E B2RXH2 3/20 1.00
▸ MAPT P10636 7/20 0.71
▸ THRB P10828 1/20 0.71
▸ SMN1; SMN2 Q16637 1/20 0.71
▸ GAA P10253 1/20 0.61
▸ CXCL12 P48061 1/20 0.61
▸ CTSL P07711 1/20 0.58
▸ MAOB P27338 3/20 0.58
▸ POLB P06746 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ P4HB P07237 1/20 0.56
▸ CALM1 P0DP23 1/20 0.56
▸ RAB9A P51151 1/20 0.56
▸ F3 P13726 1/20 0.56
▸ XDH P47989 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383756 1.00 KMT2A (1.00) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL25198797 0.92 MEN1 (0.86) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL25195235 0.90 MEN1 (0.82) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL25207663 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL31233173 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL31233297 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL25193921 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL25234254 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL25223772 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E
SCHEMBL30383816 0.89 MEN1 (0.81) KMT2AMEN1ALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B KMT2A 2792/4885MEN1 3367/4885ALDH1A1 3285/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885ALDH1A1 3081/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885ALDH1A1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback