⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31271521 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL16784554 | 0.72 | NPSR1 (0.56) | — | |
| SCHEMBL13028437 | 0.69 | — | — | |
| SCHEMBL4159602 | 0.67 | NPSR1 (0.46) | — | |
| SCHEMBL8950863 | 0.67 | — | — | |
| SCHEMBL8950836 | 0.67 | — | — | |
| SCHEMBL2880722 | 0.65 | — | — | |
| SCHEMBL24682898 | 0.63 | NPSR1 (0.39) | — | |
| SCHEMBL30301007 | 0.63 | — | — | |
| SCHEMBL25189500 | 0.62 | NPSR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353854-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN | BIOMEA FUSION INC (US) | 2025-11-20 | — | — | US | disclosed |
| US-20250066386-A1 | INHIBITORS OF KRAS | BIOMEA FUSION, INC. | 2025-02-27 | — | — | US | disclosed |
| WO-2023235618-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN | BIOMEA FUSION, INC. (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023086341-A1 | INHIBITORS OF KRAS | BIOMEA FUSION, INC. (US) | 2023-05-19 | — | — | WO | disclosed |