SCHEMBL25192190

SCHEMBL25192190

COc1cc(O)c(C(=O)/C=C/c2ccc(OCc3ccccc3)cc2)c(OC)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.77
▸ KMT2A Q03164 4/20 0.77
▸ CYP3A4 P08684 3/20 0.77
▸ TP53 P04637 2/20 0.77
▸ ATM Q13315 1/20 0.77
▸ HSD17B10 Q99714 1/20 0.77
▸ ABCG2 Q9UNQ0 5/20 0.74
▸ SLC5A1 P13866 1/20 0.73
▸ SLC5A2 P31639 1/20 0.73
▸ APP P05067 1/20 0.71
▸ NFKB1 P19838 1/20 0.71
▸ DPP4 P27487 1/20 0.71
▸ NFKB2 Q00653 1/20 0.71
▸ RELA Q04206 1/20 0.71
▸ MKNK2 Q9HBH9 1/20 0.69
▸ MAOB P27338 3/20 0.67
▸ MEN1 O00255 3/20 0.65
▸ KDM4E B2RXH2 2/20 0.65
▸ HPGD P15428 2/20 0.65
▸ TDP1 Q9NUW8 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25264975 1.00 MAPT (0.77) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL25285427 0.92 MAPT (0.78) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL25234616 0.91 SLC5A1 (0.70) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL17237771 0.91 SLC5A1 (0.70) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL30383596 0.89 ABCG2 (0.76) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL5433412 0.89 ABCG2 (0.76) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL30384422 0.89 ABCG2 (0.76) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL25193887 0.89 ABCG2 (0.76) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL25192256 0.89 ABCG2 (0.76) MAPTKMT2ACYP3A4TP53ATM
SCHEMBL5433415 0.89 ABCG2 (0.76) MAPTKMT2ACYP3A4TP53ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885KMT2A 2792/4885CYP3A4 928/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885CYP3A4 1589/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885CYP3A4 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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