SCHEMBL2519220

SCHEMBL2519220

C=C([SiH3])C(N(C)C(C)=O)N(C)C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8776517 0.73
SCHEMBL233892 0.69
SCHEMBL27721762 0.65
SCHEMBL2785653 0.64 CHRM2 (0.35)
SCHEMBL498297 0.64
SCHEMBL11406767 0.62 ALDH1A1 (0.30)
SCHEMBL8221605 0.61
SCHEMBL18466909 0.61
SCHEMBL177629 0.61
SCHEMBL14372546 0.60 CHRM2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9502234-B2 Methods to prepare silicon-containing films AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-11-22 US disclosed
US-20150249007-A1 Methods to Prepare Silicon-Containing Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-09-03 US disclosed
US-8703625-B2 Methods to prepare silicon-containing films AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-04-22 US disclosed
US-20110215445-A1 Methods to Prepare Silicon-Containing Films AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-09-08 US disclosed
EP-2363512-A1 Methods to prepare silicon-containing films AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-09-07 EP disclosed
EP-0542485-B1 Radiation curable compositions DOW CORNING (GB) 1997-06-11 EP disclosed
EP-0542484-B1 Organosilicon compounds and compositions containing them DOW CORNING (GB) 1997-01-02 EP disclosed
US-5331020-A Organosilicon compounds and compositions containing them DOW CORNING LIMITED (GB) 1994-07-19 US disclosed
US-5270423-A Organosilicon compounds and compositions containing them DOW CORNING LIMITED (GB) 1993-12-14 US disclosed
US-5238988-A Rapid cure room temperature vulcanizable organosiloxane compositions DOW CORNING CORPORATION (US) 1993-08-24 US disclosed
EP-0542484-A1 Organosilicon compounds and compositions containing them Dow Corning Limited (GB) 1993-05-19 EP disclosed
EP-0542485-A1 Radiation curable compositions Dow Corning Limited (GB) 1993-05-19 EP disclosed
EP-0029291-B1 METHOD FOR PREPARING A PRECURED SILICONE EMULSION DOW CORNING CORPORATION (US) 1983-01-26 EP disclosed
US-4273634-A VINYLSILOXANE GROUPS DOW CORNING CORPORATION (US) 1981-06-16 US disclosed
WO-1981001411-A1 A PRECURED SILICONE EMULSION AND METHOD FOR PREPARATION DOW CORNING (US) 1981-05-28 WO disclosed
EP-0029291-A1 Method for preparing a precured silicone emulsion DOW CORNING CORPORATION (US) 1981-05-27 EP disclosed
US-3997497-A Room temperature-curable organopolysiloxane compositions SHIN-ETSU CHEMICAL CO., LTD. (JA) 1976-12-14 US disclosed