Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.45 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25192518 | 1.00 | PPARA (0.48) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL30441268 | 0.87 | CTSK (0.44) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL29376464 | 0.84 | PPARA (0.50) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL7991202 | 0.82 | PPARA (0.48) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL15129729 | 0.82 | PPARA (0.48) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL4388129 | 0.82 | PPARA (0.48) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL4705351 | 0.80 | PPARA (0.51) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL30361297 | 0.80 | PPARA (0.51) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL580779 | 0.79 | PPARA (0.53) | PPARAPPARGCTSKCTSSCTSL | |
| SCHEMBL212031 | 0.79 | PPARA (0.53) | PPARAPPARGCTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086498-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2023-05-19 | — | — | WO | disclosed |