SCHEMBL580779

SCHEMBL580779

COC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 6/20 0.53
CTSS P25774 10/20 0.53
CTSK P43235 8/20 0.53
PPARG P37231 5/20 0.51
CTSL P07711 2/20 0.50
CTSB P07858 2/20 0.50
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
ACE P12821 1/20 0.46
PPARD Q03181 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL588912 1.00 PPARA (0.53) PPARACTSSCTSKPPARGCTSL
SCHEMBL527131 1.00 PPARA (0.53) PPARACTSSCTSKPPARGCTSL
SCHEMBL8130419 0.95 PPARA (0.50) PPARACTSSCTSKPPARGCTSL
SCHEMBL30448077 0.88 PPARA (0.50) PPARACTSSCTSKPPARGCTSL
SCHEMBL1278066 0.88 PPARA (0.53) PPARACTSSCTSKPPARGCTSL
SCHEMBL27398769 0.87 PPARA (0.55) PPARACTSSCTSKPPARGCTSL
SCHEMBL27398770 0.87 PPARA (0.55) PPARACTSSCTSKPPARGCTSL
SCHEMBL25262348 0.86 CTSK (0.48) PPARACTSSCTSKPPARGCTSL
SCHEMBL953455 0.86 CTSK (0.48) PPARACTSSCTSKPPARGCTSL
SCHEMBL953453 0.86 CTSK (0.48) PPARACTSSCTSKPPARGCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
EP-4720058-A2 BIFUNCTIONAL DEGRADERS AND USES THEREOF Casma Therapeutics, Inc. (US) 2026-04-08 EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4678238-A2 ARGINASE INHIBITORS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2026-01-14 EP disclosed
US-12486262-B2 Compounds and uses thereof FOGHORN THERAPEUTICS INC. (US) 2025-12-02 US disclosed
EP-4651947-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651946-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651945-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651948-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651953-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-1998035982-A1 COMPOUNDS FOR USE IN ADEPT ZENECA LIMITED (GB) 1998-08-20 WO disclosed
WO-1997027304-A9 PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA 1997-10-09 WO disclosed
WO-1997027304-A1 PARA-NITROBENZYL ESTERASES WITH ENHANCED ACTIVITY IN AQUEOUS AND NONAQUEOUS MEDIA CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1997-07-31 WO disclosed
EP-0122018-B1 IMPROVEMENTS IN AND RELATING TO PHARMACOLOGICALLY ACTIVE TRIPEPTIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1987-09-02 EP disclosed
US-4517379-A ARTIFICIAL SWEETENER PFIZER INC. (US) 1985-05-14 US disclosed
EP-0069811-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-10-24 EP disclosed
EP-0122018-A2 Improvements in and relating to pharmacologically active tripeptide derivatives ELI LILLY AND COMPANY (US) 1984-10-17 EP disclosed
US-4454328-A SWEETENERS PFIZER INC. (US) 1984-06-12 US disclosed
US-4399163-A ARTIFICIAL SWEETENERS PFIZER INC. (US) 1983-08-16 US disclosed
EP-0069811-A1 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1983-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 PPARA 2794/4885CTSS 4022/4885CTSK 4661/4885
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof SUMO1, SUMO3, PSMB6 PPARA 3869/4885CTSS 1281/4885CTSK 2087/4885
US-12486262-B2 Compounds and uses thereof VHL, CLN6, TFEB PPARA 1483/4885CTSS 2010/4885CTSK 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.