SCHEMBL25195693

SCHEMBL25195693

CCOc1ccc(C(=O)C=Cc2ccc(OC)c(O)c2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.82
▸ KDM4E B2RXH2 2/20 0.82
▸ LMNA P02545 2/20 0.82
▸ MAOB P27338 7/20 0.70
▸ ALDH1A1 P00352 1/20 0.70
▸ SMN1; SMN2 Q16637 1/20 0.70
▸ ABCG2 Q9UNQ0 1/20 0.67
▸ PDE4A P27815 1/20 0.66
▸ PDE4B Q07343 1/20 0.66
▸ PDE4C Q08493 1/20 0.66
▸ PDE4D Q08499 1/20 0.66
▸ CXCL12 P48061 1/20 0.64
▸ TUBB4A P04350 1/20 0.64
▸ TUBB P07437 1/20 0.64
▸ TUBA3C P0DPH7 1/20 0.64
▸ TUBA1B P68363 1/20 0.64
▸ TUBA4A P68366 1/20 0.64
▸ TUBB4B P68371 1/20 0.64
▸ TUBB3 Q13509 1/20 0.64
▸ TUBB2A Q13885 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25192718 1.00 MAPT (0.82) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL25209423 0.91 ABCG2 (0.68) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL30382999 0.91 ABCG2 (0.68) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL19782817 0.90 KDM4E (0.82) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL25190989 0.90 KDM4E (0.82) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL31233026 0.89 CXCL12 (0.80) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL25195682 0.89 CXCL12 (0.80) MAPTKDM4ELMNAMAOBALDH1A1
SCHEMBL30384079 0.88 TUBB1 (0.79) ABCG2PDE4APDE4BPDE4CPDE4D
SCHEMBL25196076 0.88 TUBB1 (0.79) ABCG2PDE4APDE4BPDE4CPDE4D
SCHEMBL25199746 0.88 LMNA (0.64) MAPTKDM4ELMNAALDH1A1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885KDM4E 1732/4885LMNA 1180/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KDM4E 2652/4885LMNA 1817/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KDM4E 2652/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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