Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356666 | 1.00 | FFAR1 (0.32) | FFAR1AAK1EGFRITK | |
| SCHEMBL25193890 | 0.87 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL29640830 | 0.85 | ROCK2 (0.38) | FFAR1AAK1EGFRITK | |
| SCHEMBL29627860 | 0.85 | ROCK2 (0.38) | FFAR1AAK1EGFRITK | |
| SCHEMBL25195353 | 0.85 | ROCK2 (0.38) | FFAR1AAK1EGFRITK | |
| SCHEMBL26289893 | 0.84 | CCNT1 (0.32) | EGFRITK | |
| SCHEMBL26289941 | 0.82 | JAK3 (0.32) | EGFRITK | |
| SCHEMBL26289972 | 0.79 | KDM4E (0.34) | — | |
| SCHEMBL25192876 | 0.79 | FFAR1 (0.35) | FFAR1AAK1 | |
| SCHEMBL30356727 | 0.79 | FFAR1 (0.35) | FFAR1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295131-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | ANGION BIOMEDICA CORP. | 2023-09-21 | — | — | US | disclosed |
| US-20230295131-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | ANGION BIOMEDICA CORP. | 2023-09-21 | — | — | US | disclosed |
| US-20230295131-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | ANGION BIOMEDICA CORP. | 2023-09-21 | — | — | US | disclosed |
| EP-4185579-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | Angion Biomedica Corp. (US) | 2023-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295131-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | ROCK1, ROCK2, RHOA | FFAR1 2938/4885AAK1 1335/4885EGFR 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.