SCHEMBL25196895

SCHEMBL25196895

CCOc1cc(/C=C/C(=O)c2ccc(F)cc2)ccc1O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 9/20 0.75
MAOB P27338 1/20 0.67
TOP2A P11388 1/20 0.66
PDE4A P27815 1/20 0.64
PDE4B Q07343 1/20 0.64
PDE4C Q08493 1/20 0.64
PDE4D Q08499 1/20 0.64
LMNA P02545 3/20 0.58
MAPT P10636 2/20 0.58
KDM4E B2RXH2 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
POLB P06746 1/20 0.57
CXCR4 P61073 1/20 0.57
RELA Q04206 1/20 0.57
ALDH1A1 P00352 2/20 0.56
KRAS P01116 1/20 0.56
ATM Q13315 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384897 1.00 CXCL12 (0.75) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL30383555 1.00 CXCL12 (0.75) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL25188829 1.00 CXCL12 (0.75) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL11342203 0.90 LMNA (0.69) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL11342200 0.90 LMNA (0.69) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL25221493 0.89 MAPT (0.73) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL25216640 0.89 CXCL12 (0.74) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL30383313 0.89 MAPT (0.73) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL25219819 0.89 CXCL12 (0.74) CXCL12MAOBTOP2APDE4APDE4B
SCHEMBL30384133 0.89 CXCL12 (0.74) CXCL12MAOBTOP2APDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CXCL12 399/4885MAOB 1004/4885TOP2A 4354/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CXCL12 287/4885MAOB 2435/4885TOP2A 4555/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CXCL12 287/4885MAOB 2435/4885TOP2A 4555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.