SCHEMBL25199000

SCHEMBL25199000

CCOc1ccc(C(=O)/C=C/c2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 11/20 1.00
▸ ABCG2 Q9UNQ0 3/20 1.00
▸ MAPT P10636 4/20 0.76
▸ RAB9A P51151 2/20 0.76
▸ KMT2A Q03164 2/20 0.76
▸ MAOA P21397 1/20 0.76
▸ NPC1 O15118 1/20 0.76
▸ KDM4E B2RXH2 1/20 0.73
▸ LMNA P02545 1/20 0.73
▸ POLB P06746 1/20 0.73
▸ NPSR1 Q6W5P4 1/20 0.73
▸ CYP1A1 P04798 1/20 0.71
▸ CYP1B1 Q16678 1/20 0.71
▸ P4HB P07237 1/20 0.71
▸ CALM1 P0DP23 1/20 0.71
▸ MEN1 O00255 1/20 0.71
▸ ALDH1A1 P00352 1/20 0.71
▸ F3 P13726 1/20 0.71
▸ XDH P47989 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25205390 1.00 MAOB (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25201231 1.00 MAOB (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25265255 0.89 ABCG2 (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25193296 0.89 ABCG2 (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25218183 0.89 ABCG2 (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25218115 0.89 ABCG2 (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25195480 0.89 ABCG2 (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25264967 0.89 ABCG2 (1.00) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL25195558 0.88 MAOB (0.81) MAOBABCG2MAPTRAB9AKMT2A
SCHEMBL9818322 0.88 MAOB (1.00) MAOBABCG2MAPTRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885ABCG2 1606/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885ABCG2 3622/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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