SCHEMBL25199057

SCHEMBL25199057

Cc1nn(C)c(=O)c(-c2c(-c3ccc(F)cc3)sc3ccc(F)cc23)c1O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.34
PMM2 O15305 2/20 0.34
G6PD P11413 2/20 0.34
MPI P34949 2/20 0.34
APOBEC3G Q9HC16 2/20 0.34
CRHR1 P34998 2/20 0.34
PGR P06401 2/20 0.33
NR3C2 P08235 2/20 0.33
SPR P35270 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
POLB P06746 2/20 0.32
PKM P14618 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30254871 0.94 MIF (0.38) ESR1MPICRHR1TP53
SCHEMBL25184312 0.91 ESR1 (0.38) ESR1MPIPGRNR3C2KDM4E
SCHEMBL30389735 0.91 ESR1 (0.38) ESR1MPIPGRNR3C2KDM4E
SCHEMBL30388577 0.91 MC4R (0.41) ESR1KDM4ETSHR
SCHEMBL25184882 0.91 MIF (0.37) ESR1CRHR1SPRKDM4EALDH1A1
SCHEMBL25181426 0.91 MC4R (0.41) ESR1KDM4ETSHR
SCHEMBL28661730 0.90 GPR139 (0.35) ESR1PMM2MPIAPOBEC3GCRHR1
SCHEMBL28661087 0.78 MAPK8 (0.36) CRHR1MAPTTHRBHSP90AA1LMNA
SCHEMBL28665444 0.76 MEN1 (0.39) KDM4EHSP90AA1L3MBTL1KDM4C
SCHEMBL17224805 0.75 PLA2G10 (0.38) SPRKDM4EMAPTPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304990-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 US disclosed
CN-118265781-A Herbicide resistance 先正达农作物保护股份公司 2024-06-28 CN disclosed
WO-2023083972-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2023-05-19 WO disclosed