Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25184882 | 0.86 | MIF (0.37) | MEN1KMT2AATMKDM4CKDM4E | |
| SCHEMBL28666652 | 0.86 | UBE2N (0.37) | MEN1KMT2AATMKDM4CSLC11A2 | |
| SCHEMBL29384893 | 0.86 | UBE2N (0.37) | MEN1KMT2AATMKDM4CSLC11A2 | |
| SCHEMBL30388992 | 0.82 | L3MBTL1 (0.49) | MEN1KMT2AATMPLA2G10L3MBTL1 | |
| SCHEMBL25187858 | 0.82 | L3MBTL1 (0.49) | MEN1KMT2AATMPLA2G10L3MBTL1 | |
| SCHEMBL25184312 | 0.76 | ESR1 (0.38) | KDM4ECASP3 | |
| SCHEMBL25199057 | 0.76 | ESR1 (0.34) | KDM4CL3MBTL1HSP90AA1KDM4E | |
| SCHEMBL30389735 | 0.76 | ESR1 (0.38) | KDM4ECASP3 | |
| SCHEMBL30254871 | 0.73 | MIF (0.38) | — | |
| SCHEMBL25181426 | 0.71 | MC4R (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825398-A | Pyridazinone compounds and herbicides | 日产化学株式会社 | 2021-12-21 | — | — | CN | disclosed |