Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030554 | 0.85 | NR4A2 (0.67) | CYSLTR1SPHK2SPHK1MRGPRX4FFAR1 | |
| SCHEMBL30391934 | 0.83 | SPHK2 (0.48) | SPHK2SPHK1MRGPRX4FFAR1MAOB | |
| SCHEMBL25720523 | 0.83 | SPHK2 (0.48) | SPHK2SPHK1MRGPRX4FFAR1MAOB | |
| SCHEMBL20788374 | 0.82 | CYSLTR1 (0.56) | CYSLTR1MRGPRX4FFAR1MAOBNPC1 | |
| SCHEMBL6244114 | 0.80 | PTGER1 (0.55) | CYSLTR1MRGPRX4FFAR1MAOBNPC1 | |
| SCHEMBL15607572 | 0.79 | FFAR1 (0.52) | SPHK2SPHK1FFAR1MAOBNPC1 | |
| SCHEMBL24502891 | 0.78 | SMPD1 (0.53) | CYSLTR1MRGPRX4MAOBNPC1RAB9A | |
| SCHEMBL6206160 | 0.78 | SPHK2 (0.50) | SPHK2SPHK1MRGPRX4FFAR1MAOB | |
| SCHEMBL6206165 | 0.78 | SPHK2 (0.50) | SPHK2SPHK1MRGPRX4FFAR1MAOB | |
| SCHEMBL6206166 | 0.78 | SPHK2 (0.50) | SPHK2SPHK1MRGPRX4FFAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051300-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-02-13 | — | — | US | disclosed |
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023091873-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051300-A1 | GRAM-NEGATIVE SPECIFIC ANTIBIOTICS SPARING EFFECT ON GUT MICROBIOME | ABCE1, LDLR, LIPE | CYSLTR1 2982/4885SPHK2 1474/4885SPHK1 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.