Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940101 | 0.99 | POLB (0.42) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL23276497 | 0.87 | POLB (0.37) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL28412554 | 0.86 | NLRP3 (0.42) | POLBALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8868958 | 0.86 | POLB (0.50) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL23276333 | 0.85 | POLB (0.38) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL28533502 | 0.85 | NLRP3 (0.39) | POLBALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL20484021 | 0.85 | CYP1A2 (0.42) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL7021898 | 0.83 | POLB (0.45) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL8961970 | 0.83 | MEN1 (0.39) | POLBALDH1A1ALOX12HTTMEN1 | |
| SCHEMBL15995052 | 0.81 | GAA (0.44) | POLBALDH1A1ALOX12HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | disclosed |