Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767825 | 0.77 | CRBN (0.48) | — | |
| SCHEMBL22162915 | 0.75 | AHR (0.37) | AHR | |
| SCHEMBL25208442 | 0.70 | GPR139 (0.38) | AHR | |
| SCHEMBL24820619 | 0.70 | KCNH2 (0.38) | — | |
| SCHEMBL24819773 | 0.68 | KCNH2 (0.39) | — | |
| SCHEMBL25200954 | 0.67 | GPR139 (0.35) | AHR | |
| SCHEMBL119040 | 0.64 | AOC3 (0.37) | — | |
| SCHEMBL22098778 | 0.61 | GPR139 (0.38) | — | |
| SCHEMBL20049608 | 0.61 | USP30 (0.42) | AHR | |
| SCHEMBL16439323 | 0.61 | CHEK1 (0.45) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034134-A1 | 15-PGDH INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-01-30 | — | — | US | disclosed |
| EP-4434986-A1 | 15-PGDH INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023088425-A1 | 15-PGDH INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-05-25 | — | — | WO | disclosed |
| WO-2023088425-A1 | 15-PGDH INHIBITOR AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-05-25 | — | — | WO | disclosed |
| CN-116135856-A | 15-PGDH inhibitor and application thereof | 武汉人福创新药物研发中心有限公司 | 2023-05-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034134-A1 | 15-PGDH INHIBITOR AND USE THEREOF | HPGD, UGDH, PGD | AHR 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.