SCHEMBL25199731

SCHEMBL25199731

O=C(C=Cc1ccc(OCc2ccccc2)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 1.00
MAOB P27338 5/20 0.81
GSK3B P49841 3/20 0.70
BACE1 P56817 3/20 0.70
SLC5A1 P13866 1/20 0.69
SLC5A2 P31639 1/20 0.69
KMT2A Q03164 4/20 0.66
MAPT P10636 3/20 0.66
CYP3A4 P08684 2/20 0.66
HSPD1 P10809 2/20 0.66
HSPE1 P61604 2/20 0.66
MEN1 O00255 2/20 0.66
RAB9A P51151 2/20 0.66
MAOA P21397 2/20 0.66
PKM P14618 1/20 0.66
NFKB1 P19838 1/20 0.66
NFKB2 Q00653 1/20 0.66
RELA Q04206 1/20 0.66
ALDH2 P05091 1/20 0.66
CYP19A1 P11511 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25223265 1.00 ABCG2 (1.00) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL16242555 0.93 ABCG2 (0.87) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL16242554 0.93 ABCG2 (0.87) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL976816 0.90 MAOB (0.81) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL25198204 0.90 ABCG2 (0.81) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL981324 0.90 ABCG2 (0.81) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL981325 0.90 ABCG2 (0.81) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL976815 0.90 MAOB (0.81) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL25195854 0.87 ABCG2 (0.77) ABCG2MAOBGSK3BBACE1SLC5A1
SCHEMBL2647326 0.86 MAOB (0.76) ABCG2MAOBGSK3BBACE1SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MAOB 1004/4885GSK3B 193/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885GSK3B 1167/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MAOB 2435/4885GSK3B 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.