Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.87 |
| ▸ | MAOB | P27338 | 3/20 | 0.82 |
| ▸ | GSK3B | P49841 | 3/20 | 0.74 |
| ▸ | BACE1 | P56817 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.70 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16242555 | 1.00 | ABCG2 (0.87) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL25223265 | 0.93 | ABCG2 (1.00) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL25199731 | 0.93 | ABCG2 (1.00) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL976815 | 0.91 | MAOB (0.81) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL25198204 | 0.91 | ABCG2 (0.81) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL981324 | 0.91 | ABCG2 (0.81) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL981325 | 0.91 | ABCG2 (0.81) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL976816 | 0.91 | MAOB (0.81) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL2992666 | 0.91 | ABCG2 (0.73) | ABCG2MAOBGSK3BBACE1KMT2A | |
| SCHEMBL30383247 | 0.91 | MAOB (0.73) | ABCG2MAOBGSK3BBACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230011131-A1 | NOVEL COMPOUND FOR INHIBITING HISTONE ACETYLTRANSFERASE P300 AND ANTI-FIBROSIS COMPOSITION COMPRISING SAME | REFURE LIFE SCIENCE, INC. (KR) | 2023-01-12 | — | — | US | disclosed |
| US-9085520-B2 | Composition for treating diabetes and metabolic diseases and a preparation method thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-9085520-B2 | Composition for treating diabetes and metabolic diseases and a preparation method thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-9085520-B2 | Composition for treating diabetes and metabolic diseases and a preparation method thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-20140350304-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350304-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140350304-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230011131-A1 | NOVEL COMPOUND FOR INHIBITING HISTONE ACETYLTRANSFERASE P300 AND ANTI-FIBROSIS COMPOSITION COMPRISING SAME | EP300, HDAC1, KAT2A | ABCG2 4145/4885MAOB 4217/4885GSK3B 2770/4885 |
| US-20140350304-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | FABP1, GYS2, CYP7B1 | ABCG2 186/4885MAOB 3332/4885GSK3B 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.