Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22504169 | 0.66 | ACE (0.32) | ACE | |
| SCHEMBL21827453 | 0.63 | MAPT (0.34) | MAPT | |
| SCHEMBL26288597 | 0.63 | ACE (0.35) | MAPTACEKMT2A | |
| SCHEMBL16530147 | 0.62 | GRM5 (0.36) | MAPTHTTESR1MEN1KMT2A | |
| SCHEMBL13516883 | 0.62 | GRM5 (0.36) | MAPTHTTESR1MEN1KMT2A | |
| SCHEMBL22744724 | 0.60 | BRD4 (0.31) | — | |
| SCHEMBL6218830 | 0.60 | MAPT (0.33) | MAPTACEESR1MEN1KMT2A | |
| SCHEMBL6999553 | 0.60 | P2RX7 (0.40) | ACEHTTMEN1KMT2A | |
| SCHEMBL288353 | 0.60 | P2RX7 (0.40) | ACEHTTMEN1KMT2A | |
| SCHEMBL22743989 | 0.60 | BRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188551-A1 | ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF | Bayer Aktiengesellschaft (DE) | 2023-06-07 | — | — | EP | disclosed |