Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25202245 | 0.82 | DDR1 (0.52) | DDR1TRPA1LOXL2PYGLPYGM | |
| SCHEMBL16093766 | 0.81 | ALDH1A1 (0.52) | DDR1TRPA1LOXL2FTOALKBH2 | |
| SCHEMBL25552436 | 0.79 | DDR1 (0.52) | DDR1TRPA1LOXL2FTOALKBH2 | |
| SCHEMBL30595870 | 0.78 | KDR (0.54) | DDR1FTOALKBH2ALKBH5ALKBH3 | |
| SCHEMBL18422426 | 0.78 | KDR (0.54) | DDR1FTOALKBH2ALKBH5ALKBH3 | |
| SCHEMBL29537506 | 0.77 | KDM4E (0.55) | EGLN1FTOALKBH2ALKBH5ALKBH3 | |
| SCHEMBL222146 | 0.77 | KDM4E (0.55) | EGLN1FTOALKBH2ALKBH5ALKBH3 | |
| SCHEMBL171037 | 0.77 | EGLN1 (0.55) | EGLN1FTOEGLN2MMP13 | |
| SCHEMBL5926500 | 0.77 | GCGR (0.57) | EGLN1MMP13 | |
| SCHEMBL30717932 | 0.76 | EGLN1 (0.46) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |