Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | CBLB | Q13191 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25552436 | 0.89 | DDR1 (0.52) | DDR1ALDH1A1GAAL3MBTL1LOXL2 | |
| SCHEMBL25199807 | 0.82 | DDR1 (0.51) | DDR1LOXL2ANO1TRPA1GLS | |
| SCHEMBL31461288 | 0.79 | FAP (0.48) | — | |
| SCHEMBL30637929 | 0.79 | FAP (0.48) | ALDH1A1MAPT | |
| SCHEMBL30637965 | 0.79 | FAP (0.48) | — | |
| SCHEMBL25184672 | 0.78 | ACKR3 (0.43) | DDR1TRPA1GLSRAF1ACKR3 | |
| SCHEMBL5803117 | 0.76 | PTPRC (0.54) | PTPRC | |
| SCHEMBL16093766 | 0.76 | ALDH1A1 (0.52) | DDR1ALDH1A1GAAL3MBTL1LOXL2 | |
| SCHEMBL18422426 | 0.76 | KDR (0.54) | DDR1ALDH1A1GAAL3MBTL1GLS | |
| SCHEMBL30595870 | 0.76 | KDR (0.54) | DDR1ALDH1A1GAAL3MBTL1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |