SCHEMBL25200433

SCHEMBL25200433

O=C(O)COc1ccc(/C=C/C(=O)c2ccc(F)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.73
KMT2A Q03164 4/20 0.67
MEN1 O00255 3/20 0.67
TNFRSF1A P19438 1/20 0.67
NPC1 O15118 2/20 0.65
RAB9A P51151 2/20 0.65
POLB P06746 1/20 0.65
BLM P54132 1/20 0.65
GPR35 Q9HC97 1/20 0.65
MAOA P21397 1/20 0.57
MAPT P10636 1/20 0.57
CYP1A1 P04798 1/20 0.56
CYP1B1 Q16678 1/20 0.56
ABCG2 Q9UNQ0 2/20 0.56
CYSLTR1 Q9Y271 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25210712 1.00 MAOB (0.73) MAOBKMT2AMEN1TNFRSF1ANPC1
SCHEMBL11459733 0.93 KMT2A (0.75) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11459734 0.93 KMT2A (0.75) MAOBKMT2AMEN1NPC1RAB9A
Cinfenoac SCHEMBL1516598 0.89 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
Cinfenoac SCHEMBL25209635 0.89 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11452470 0.89 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11452467 0.89 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
Cinfenoac SCHEMBL10543583 0.89 KMT2A (0.70) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11451943 0.87 KMT2A (0.68) MAOBKMT2AMEN1NPC1RAB9A
SCHEMBL11451947 0.87 KMT2A (0.68) MAOBKMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885KMT2A 2792/4885MEN1 3367/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885KMT2A 3188/4885MEN1 2457/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885KMT2A 3188/4885MEN1 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.