SCHEMBL25200524

SCHEMBL25200524

Nc1ccc(S(=O)(=O)Oc2ccc(C(=O)C=Cc3ccc(O)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
F3 P13726 2/20 0.56
RAB9A P51151 2/20 0.56
P4HB P07237 1/20 0.56
CALM1 P0DP23 1/20 0.56
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
XDH P47989 1/20 0.56
KMT2A Q03164 1/20 0.56
ABCG2 Q9UNQ0 4/20 0.53
MAOB P27338 3/20 0.53
STS P08842 1/20 0.53
CYP1B1 Q16678 1/20 0.51
BCHE P06276 1/20 0.51
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
CXCL12 P48061 1/20 0.50
POLB P06746 1/20 0.50
MAOA P21397 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13434634 1.00 MAPT (0.56) MAPTF3RAB9AP4HBCALM1
SCHEMBL13434671 0.94 F3 (0.64) MAPTF3RAB9AP4HBCALM1
SCHEMBL25189348 0.94 F3 (0.64) MAPTF3RAB9AP4HBCALM1
SCHEMBL13434628 0.88 TNFRSF1A (0.58) MAPTF3RAB9AP4HBCALM1
SCHEMBL25190545 0.88 MAOB (0.68) MAPTF3RAB9AP4HBCALM1
SCHEMBL25199779 0.88 MAOB (0.68) MAPTF3RAB9AP4HBCALM1
SCHEMBL25284855 0.88 TNFRSF1A (0.58) MAPTF3RAB9AP4HBCALM1
SCHEMBL13434627 0.88 MAOB (0.68) MAPTF3RAB9AP4HBCALM1
SCHEMBL13434635 0.88 KMT2A (0.62) MAPTF3RAB9AP4HBCALM1
SCHEMBL25202161 0.88 KMT2A (0.62) MAPTF3RAB9AP4HBCALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885F3 5/4885RAB9A 480/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885F3 11/4885RAB9A 1327/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885F3 11/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.