SCHEMBL25199779

SCHEMBL25199779

Cc1ccc(S(=O)(=O)Oc2ccc(/C=C/C(=O)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.68
MAPT P10636 4/20 0.68
MAOA P21397 3/20 0.68
RAB9A P51151 2/20 0.68
POLB P06746 1/20 0.68
F3 P13726 2/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
P4HB P07237 1/20 0.60
CALM1 P0DP23 1/20 0.60
ALDH1A1 P00352 1/20 0.60
XDH P47989 1/20 0.60
PTPN1 P18031 1/20 0.59
ABCG2 Q9UNQ0 3/20 0.56
BCHE P06276 1/20 0.54
CYP1B1 Q16678 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13434627 1.00 MAOB (0.68) MAOBMAPTMAOARAB9APOLB
SCHEMBL25190545 1.00 MAOB (0.68) MAOBMAPTMAOARAB9APOLB
SCHEMBL25189348 0.94 F3 (0.64) MAOBMAPTMAOARAB9APOLB
SCHEMBL13434671 0.94 F3 (0.64) MAOBMAPTMAOARAB9APOLB
SCHEMBL27755220 0.89 MAPT (0.68) MAOBMAPTMAOARAB9APOLB
SCHEMBL3890673 0.89 MAPT (0.68) MAOBMAPTMAOARAB9APOLB
SCHEMBL25200524 0.88 MAPT (0.56) MAOBMAPTMAOARAB9APOLB
SCHEMBL13434634 0.88 MAPT (0.56) MAOBMAPTMAOARAB9APOLB
SCHEMBL25284855 0.88 TNFRSF1A (0.58) MAOBMAPTMAOARAB9AF3
SCHEMBL13434628 0.88 TNFRSF1A (0.58) MAOBMAPTMAOARAB9AF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885MAPT 3297/4885MAOA 1902/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAPT 3512/4885MAOA 3145/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAPT 3512/4885MAOA 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.