SCHEMBL25200543

SCHEMBL25200543

Nc1ccccc1C(=O)/C=C/c1ccc(O)c(O)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.75
KMT2A Q03164 3/20 0.75
PTGS1 P23219 2/20 0.75
PTGS2 P35354 2/20 0.75
KDM4E B2RXH2 1/20 0.75
GAA P10253 1/20 0.75
MAPK1 P28482 1/20 0.75
NPSR1 Q6W5P4 1/20 0.75
MYOC Q99972 1/20 0.75
TERT O14746 2/20 0.61
MEN1 O00255 2/20 0.61
NFKB1 P19838 2/20 0.61
NFKB2 Q00653 2/20 0.61
RELA Q04206 2/20 0.61
NPC1 O15118 1/20 0.61
LMNA P02545 1/20 0.61
PKM P14618 1/20 0.61
HPGD P15428 1/20 0.61
ALOX12 P18054 1/20 0.61
RAB9A P51151 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382983 0.86 MAPT (0.77) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL8847550 0.86 MAPT (0.77) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL8847553 0.86 MAPT (0.77) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL5508056 0.86 MAPT (1.00) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL4973168 0.86 MAPT (1.00) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL25192703 0.86 MAPT (1.00) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL31233153 0.86 MAPT (1.00) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL14801690 0.84 MAPT (0.65) MAPTKMT2APTGS1PTGS2KDM4E
SCHEMBL25225496 0.83 MAPT (0.78) MAPTKMT2AKDM4EMAPK1NPSR1
SCHEMBL25190631 0.83 MAPT (0.78) MAPTKMT2AKDM4EMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885KMT2A 2792/4885PTGS1 522/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885PTGS1 180/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885PTGS1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.