Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 13/20 | 0.49 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30348906 | 1.00 | LRRK2 (0.49) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL30347892 | 0.89 | LRRK2 (0.46) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL25204231 | 0.89 | LRRK2 (0.46) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL30400624 | 0.85 | ROCK2 (0.52) | LRRK2ROCK2ROCK1CDC42BPBTDO2 | |
| SCHEMBL26174628 | 0.85 | ROCK2 (0.52) | LRRK2ROCK2ROCK1CDC42BPBTDO2 | |
| SCHEMBL25203990 | 0.83 | LRRK2 (0.53) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL25158143 | 0.81 | LRRK2 (0.50) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL30349516 | 0.80 | EGFR (0.50) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL25201354 | 0.80 | EGFR (0.50) | LRRK2JAK3ROCK2ROCK1CDC42BPB | |
| SCHEMBL30400374 | 0.80 | ALK (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129104-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | TENARX, INC. | 2025-04-24 | — | — | US | claimed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | claimed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | LRRK2 729/4885JAK3 800/4885ROCK2 998/4885 |
| US-20250129104-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | LRRK2 729/4885JAK3 800/4885ROCK2 998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.