SCHEMBL25200829

SCHEMBL25200829

CCOC(=O)C1=C(C)C=CCC12CC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.37
ALDH1A1 P00352 5/20 0.36
HPGD P15428 2/20 0.36
HTT P42858 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HSP90AA1 P07900 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 5/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PKM P14618 1/20 0.35
CCR6 P51684 1/20 0.35
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3642091 0.94 ALDH1A1 (0.38) MAPTKDM4EMEN1KMT2AALOX15
SCHEMBL25213941 0.83 HTT (0.33) MAPTKMT2ATSHRALDH1A1HPGD
SCHEMBL754466 0.82 MAPT (0.39) MAPTKDM4EMEN1KMT2AALOX15
SCHEMBL25208706 0.79 MAPK1 (0.38) MAPTKDM4EMEN1KMT2AALOX15
SCHEMBL25201852 0.74
SCHEMBL11528099 0.70 MAPT (0.37) MAPTKDM4EMEN1KMT2AALOX15
SCHEMBL3643846 0.69
SCHEMBL29275507 0.67 KMT2A (0.35) KMT2ATSHRALDH1A1HPGDHTT
SCHEMBL3643855 0.66
SCHEMBL3642326 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4405323-B1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH & CIE (CH) 2026-01-14 EP disclosed
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2025-01-30 US disclosed
EP-4405323-A1 PROCESS FOR PREPARING A CYCLIC DIENE Firmenich SA (CH) 2024-07-31 EP disclosed
CN-118302402-A Process for the preparation of cyclic dienes 弗门尼舍有限公司 2024-07-05 CN disclosed
WO-2023094502-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2023-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE DHPS, FDFT1, CYP17A1 MAPT 2999/4885KDM4E 3254/4885MEN1 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.