Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 13/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31315517 | 1.00 | WDR5 (0.35) | WDR5KDM4EMEN1CASP1KMT2A | |
| SCHEMBL30427248 | 0.88 | WDR5 (0.36) | WDR5 | |
| SCHEMBL25199101 | 0.88 | WDR5 (0.36) | WDR5 | |
| SCHEMBL25187166 | 0.83 | WDR5 (0.54) | WDR5 | |
| SCHEMBL31315511 | 0.82 | WDR5 (0.52) | WDR5 | |
| SCHEMBL30427430 | 0.80 | WDR5 (0.51) | WDR5 | |
| SCHEMBL25264674 | 0.76 | WDR5 (0.41) | WDR5 | |
| SCHEMBL25192240 | 0.76 | WDR5 (0.41) | WDR5 | |
| SCHEMBL31315499 | 0.74 | WDR5 (0.39) | WDR5 | |
| SCHEMBL30427413 | 0.74 | WDR5 (0.39) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | disclosed |