SCHEMBL25264674

SCHEMBL25264674

CCn1cc(-c2cc(Cn3ccn(C)c3=NC(=O)O)cc3c2OCCC3=O)c(C(F)(F)F)n1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25192240 1.00 WDR5 (0.41) WDR5
SCHEMBL30427413 0.90 WDR5 (0.39) WDR5
SCHEMBL31315499 0.90 WDR5 (0.39) WDR5
SCHEMBL30427430 0.85 WDR5 (0.51) WDR5
SCHEMBL25187166 0.80 WDR5 (0.54) WDR5
SCHEMBL25187773 0.78 WDR5 (0.36) WDR5
SCHEMBL25201348 0.78 HTR1A (0.30)
SCHEMBL25201351 0.78 HTR1A (0.30)
SCHEMBL25199101 0.78 WDR5 (0.36) WDR5
SCHEMBL30427248 0.78 WDR5 (0.36) WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023090829-A1 LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF 엘젠테라퓨틱스 주식회사 2023-05-25 WO disclosed