SCHEMBL25201217

SCHEMBL25201217

Cc1nn(C)c(=O)c(-c2c(F)ccc(Cl)c2CCc2cncnc2)c1O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.31
NR3C1 P04150 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30389235 1.00 MAPT (0.34) MAPTLMNAKMT2ANR3C1
SCHEMBL24310463 0.89 GAA (0.36) MAPTLMNAKMT2A
SCHEMBL29582525 0.89 GAA (0.36) MAPTLMNAKMT2A
SCHEMBL22084636 0.89 LMNA (0.36) MAPTLMNAKMT2ANR3C1
SCHEMBL22031854 0.88 CYP1A2 (0.38) MAPTLMNA
SCHEMBL22031792 0.88 CASR (0.40) MAPTLMNAKMT2A
SCHEMBL22085782 0.87 MAPT (0.37) MAPTLMNAKMT2A
SCHEMBL25180883 0.86 GRIN2B (0.33) MAPTLMNAKMT2A
SCHEMBL30388667 0.86 GRIN2B (0.33) MAPTLMNAKMT2A
SCHEMBL25180334 0.84 MAPT (0.33) MAPTLMNAKMT2ANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304990-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 US disclosed
CN-118265781-A Herbicide resistance 先正达农作物保护股份公司 2024-06-28 CN disclosed
WO-2023083972-A1 HERBICIDE RESISTANCE SYNGENTA CROP PROTECTION AG (CH) 2023-05-19 WO disclosed