Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25180399 | 0.82 | TSHR (0.37) | NOTUMCFTRALDH1A1L3MBTL1LMNA | |
| SCHEMBL29090594 | 0.82 | NOTUM (0.40) | NOTUMCFTRCYP3A4ACHEAR | |
| SCHEMBL30867498 | 0.82 | CFTR (0.44) | NOTUMCFTRCYP3A4ACHEAR | |
| SCHEMBL25174744 | 0.82 | CFTR (0.44) | NOTUMCFTRCYP3A4ACHEAR | |
| SCHEMBL30867275 | 0.82 | NOTUM (0.40) | NOTUMCFTRCYP3A4ACHEAR | |
| SCHEMBL25180891 | 0.82 | SOS1 (0.46) | NOTUMCFTRMEN1KMT2ACYP3A4 | |
| SCHEMBL22208636 | 0.81 | NOTUM (0.42) | NOTUMCFTRCYP3A4ACHEALDH1A1 | |
| SCHEMBL25181444 | 0.77 | KMT2A (0.40) | NOTUMCFTRKMT2ANPC1ALDH1A1 | |
| SCHEMBL30271454 | 0.77 | KMT2A (0.40) | NOTUMCFTRKMT2ANPC1ALDH1A1 | |
| SCHEMBL25184371 | 0.75 | HDAC4 (0.38) | ALDH1A1L3MBTL1LMNATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132917-B1 | SUBSTITUTED ISOPHTALIC ACID DIAMIDES | BAYER AG (DE) | 2024-01-24 | — | — | EP | disclosed |
| US-20230150953-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-18 | — | — | US | disclosed |
| CN-115884967-A | Substituted isophthalic acid diamides | 拜耳公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-4132917-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | Bayer Aktiengesellschaft (DE) | 2023-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150953-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | DDT, ZDHHC2, DDAH1 | NOTUM 489/4885CFTR 1133/4885MEN1 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.