SCHEMBL25201250

SCHEMBL25201250

O=C(O)c1ccc(C(=O)/C=C/c2ccc(/C=C/C(=O)c3ccc(C(=O)O)cc3)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.74
F3 P13726 3/20 0.70
MAPT P10636 5/20 0.68
TNFRSF1A P19438 2/20 0.68
CYP1B1 Q16678 6/20 0.67
MAOB P27338 3/20 0.67
PLIN1 O60240 1/20 0.67
LMNA P02545 1/20 0.67
BCHE P06276 1/20 0.67
ACHE P22303 1/20 0.67
RECQL P46063 1/20 0.67
PLIN5 Q00G26 1/20 0.67
ABHD5 Q8WTS1 1/20 0.67
CYP3A4 P08684 4/20 0.65
TDP1 Q9NUW8 2/20 0.65
TP53 P04637 1/20 0.65
ALOX15 P16050 1/20 0.65
MAPK1 P28482 1/20 0.65
BLM P54132 1/20 0.65
CASP7 P55210 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2997295 1.00 XDH (0.74) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL2997293 1.00 XDH (0.74) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL10528715 1.00 XDH (0.74) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL25195971 1.00 XDH (0.74) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL11452558 0.98 XDH (0.72) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL11452560 0.98 XDH (0.72) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL30383101 0.98 XDH (0.72) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL1981057 0.94 CYP1B1 (0.78) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL1981056 0.94 CYP1B1 (0.78) XDHF3MAPTTNFRSF1ACYP1B1
SCHEMBL11492209 0.94 CYP1B1 (0.78) XDHF3MAPTTNFRSF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B XDH 1328/4885F3 5/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 XDH 1963/4885F3 11/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 XDH 1963/4885F3 11/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.